Proteomics Bench Scientist Job at Lancesoft INC, Andover, MA

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  • Lancesoft INC
  • Andover, MA

Job Description

Job Description

Job Description

Job Title: Proteomics Bench Scientist

Location: Andover MA 01810

Duration: 12 months 

POSITION SUMMARY

  • Candidate will be responsible for developing proteomics workflows using advanced high-resolution mass spectrometry techniques.
  • Key duties include development and optimization of sample preparation methods from cell lines and other matrices for mass spectrometry analysis and data processing with various bioinformatics tools; collaborative work with colleagues; accurately documenting all activities in an electronic lab notebook (ELN).
  • This role requires expertise in LC-MS based proteomics.
  • Experience with cell culture and cell manipulation is a plus.

 

POSITION RESPONSIBILITIES

• Applying knowledge of proteomics workflows to develop and implement optimal strategies for the preparation and analysis of cellular samples

• Working collaboratively with experts in the team to advance innovative proteomics strategies

• Employing different bioinformatics tools for data analysis and fitting

• Consistent record keeping using an electronic lab notebook (ELN)

 

ORGANIZATIONAL RELATIONSHIPS

• This hire will interact daily with the managers and 3-4 colleagues in the cross-functional team for method development, laboratory work prioritization, experiment planning and execution.

The hire might also work on common assignments with colleagues in a larger bioanalytical group at the same location, as needed.

The hire will participate in bi-weekly group meetings and other team meetings and discussions, as relevant to their work.

 

EDUCATION AND EXPERIENCE

• M.Sc 5+ years, PhD 0+ years in a relevant scientific field with a documented experience in proteomics and mass-spectrometry

 

TECHNICAL SKILLS REQUIREMENTS

Required:

• Advanced knowledge and documented expertise with mass-spectrometry based proteomics approaches: label- or label-free quantification (TMT or DIA)

• Experience with high-resolution mass-spectrometry instruments, such as Orbitraps and timsTOF

• Experience with sample preparation based on enrichment (incl. affinity purification), and universal protein extraction

• Bioinformatics skills relevant for mass-spec data search, statistical analysis and visualization

Preferable:

• Experience with membrane protein analysis and/or cell surface proteomics

• Knowledge of cell culture techniques and experience conducitng cell-based assays

 

PHYSICAL POSITION REQUIREMENTS

• Walking, taking the stairs, standing, sitting as appropriate for a laboratory-based position

Company Description

We believe in service that helps you solve a problem, move forward with a project, manage a difficult situation, or simply check something off your list.

Company Description

We believe in service that helps you solve a problem, move forward with a project, manage a difficult situation, or simply check something off your list.

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